EU CLP Regulation Expands Hazard Classes for Endocrine Disruptors and Persistent Chemicals

Regulators worldwide face the complex task of assessing hazards and risks from chemicals that may disrupt endocrine systems in humans and ecosystems. The endocrine system is a hormone-driven network essential to growth, immunity, metabolism, and reproduction, and endocrine disruptors have been linked to serious health and environmental effects, including neurological disorders and cancer. To strengthen protection, the EU has updated the CLP Regulation, introducing eight new hazard classes and criteria through amendments released March 21, 2023. Endocrine disruptor classification now follows a weight-of-evidence approach with two categories and defined mixture thresholds. Despite progress, major data gaps remain, and thousands of substances may ultimately warrant classification.

Wednesday, March 25th, at 11 am ET/8 am PT

Key Learning Objectives:  

• The growing global concern around endocrine disruptors (EDs) 
  Recognize endocrine-disrupting chemicals (EDCs) are a top regulatory priority worldwide. They interfere with hormones that regulate development, metabolism, reproduction, immunity, and neurological function. Links to cancer, developmental disorders, and wildlife impacts are driving urgent regulatory action.
  
• Identify the new EU hazard classes with emphasis on endocrine disruptors and understand their definitions, categories, and classification criteria
  
• Identifying EDs remains a complex scientific challenge 
  
• Identify mixture classification thresholds for endocrine disruptors
  
• Stay informed on evolving EU regulatory expectations
  Understand the importance of ongoing monitoring of ED, PBT/vPvB, and PMT/vPvM regulatory developments to maintain compliance and anticipate future obligations.
  

Who Should Watch:  

• Regulatory Affairs Specialist/Analysts

• Product Stewardship Officers

• Regulatory Compliance Managers

• Toxicologists

• Formulation Scientists

• Quality Assurance Managers

• Research and Development Leads

• Environmental Scientists

• Researchers

Dr. Sherry Sachdeva, PhD, UK ERT 

Sherry Sachdeva, Ph.D., is a Toxicologist and Regulatory Analyst III at Pace® Life Sciences with a strong foundation in academic research and global chemical compliance. She earned her Master’s degree in Toxicology in India and completed her Ph.D. in Biological Sciences in 2020. During her doctoral work, she continued research at King’s College London as a Newton Bhabha Fellow, reflecting her commitment to international scientific collaboration.

Dr. Sachdeva has been recognized for excellence in research and scientific communication through several distinctions, including the National Post Doctoral Fellowship from the Indian Council of Medical Research, as well as national awards for outstanding poster and oral presentations. She has authored six peer-reviewed research papers and review articles in the field of toxicology, with a focus on chemical hazards, endocrine disruption, and toxicological mechanisms.

She is certified as a UK Registered Toxicologist (UK ERT) by the Royal Society of Biology (London, UK), demonstrating her dedication to maintaining high professional standards. In her current role, she supports organizations in navigating complex and evolving global regulatory frameworks, including REACH, CLP, and emerging hazard classifications. Dr. Sachdeva is especially experienced in translating scientific evidence into clear, practical strategies for compliance and sustainable chemical management.

Add Dr. Sachdeva on LinkedIn