whitepaper

developing a hydrogel microneedle array patch

Overview:

Microneedles are an evolving technology that is set to change the way we think about transdermal drug delivery systems. As transdermal devices, microneedles offer an efficient way to administer drugs quickly and reliably via a pathway that is otherwise reserved for compounds with very specific properties. Since microneedles provide a method to bypass the stratum corneum barrier, the technology opens opportunities for a large variety of compounds to be delivered through the skin.

Explore the advantages and limitations of microarray patch technology using hydrogel dosage forms. 

Key Learning Objectives:

  • Practical considerations for developing a hydrogel microneedle array patch (MAP)

  • Defining critical quality attributes (CQA) for physical, chemical, and microbiological analytical testing 

  • Packaging and application considerations for proper administration

 


 

Author:

Karl Upman
Senior Scientist, Formulation Development

Karl Upman

Karl Upman is a Senior Scientist specializing in formulation development at Pace® Life Sciences. With over four years of experience at Pace® supporting formulation development from capsules to injectables and topicals, his skills span R&D through GMP manufacturing. Before joining Pace®, Karl worked in adjuvant and immunology formulation for animal health, applying his master's degree in organic synthetic chemistry.

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